The Pittsburgh Panthers went into halftime with a modest 21-17 lead over the No. 18 Louisville Cardinals. Unfortunately for Pitt, the Cardinals put together a dominant third quarter, and now lead the Panthers 38-21 into the fourth quarter.

Louisville set the tone immediately in the third quarter. After receiving the kickoff to open up the second half, Louisville quarterback Teddy Bridgewater completed a 75-yard pass to DeVante Parker for a touchdown, giving Louisville a 24-21 lead.

Minutes later, Louisville running back Senorice Perry capped off a five play, 68-yard drive with a 2-yard touchdown run, giving the Cardinals a 31-21 lead.

Perry added another touchdown run, a 1-yard touchdown run with 1:16 left in the third quarter. Perry's second touchdown of the quarter gave Louisville a 38-21 lead.

Pittsburgh has been held to just 233 total yards through the first three quarters.

Hope is not lost for the Panthers, though. Pitt will open the fourth quarter with a 3rd-and-3 from Louisville's 22-yard line, as the Panthers look to scratch back into the game.