Pittsburgh (2-4, 0-3) is winless in Big East play this year but looks to find a momentum building win against a MAC opponent Saturday. Senior quarterback Tino Sunseri leads a Pitt offense that scored 35 points its last time out in a losing effort against No. 18 Louisville. Sunseri has thrown for 1,750 yards and 10 touchdowns through six games this season. The Panthers' 0-3 conference mark puts them in last place in the Big East.
Buffalo (1-5, 0-3) has also struggled early on this season. The Bulls, who have lost four straight games, are coming off a 42-point drubbing at the hands of Northern Illinois. They are one of five MAC teams without a conference win.
Location: UB Stadium, Buffalo, N.Y.
Game Time: 3:30 p.m. ET
TV: Big East Network
Spread: Pittsburgh by 12