The Pittsburgh Panthers will aim to keep their bowl eligibility hopes alive when they take on the Rutgers Scarlet Knights as part of a loaded holiday weekend of college football action.

With four wins on the year and two games remaining, the Panthers will need to win both their Saturday meeting with Rutgers and next weekend's showdown with the South Florida Bulls to become bowl-eligible.

Elsewhere, the Penn State Nittany Lions will hit the field for the final time in 2012, as their season ends with a conference showdown against the Wisconsin Badgers.

The West Virginia Mountaineers, also looking to gain bowl eligibility take on the Iowa State Cyclones in a Friday afternoon meeting.

Here's the weekend's key games from the Big 12, Big Ten and Big East:

TCU Horned Frogs vs. Texas Longhorns, Nov. 22, 7:30 p.m. ET, ESPN

Syracuse Orange vs. Temple Owls, Nov. 23, 11 a.m. ET, ESPN2

Nebraska Cornhuskers vs. Iowa Hawkeyes, Nov. 23, 12 p.m. ET, ABC

West Virginia Mountaineers vs. Iowa State Cyclones, Nov. 23, 3:30 p.m. ET, ABC

South Florida Bulls vs. Cincinnati Bearcats, Nov. 23, 7 p.m. ET, ESPN

Illinois Fighting Illini vs. Northwestern Wildcats, Nov. 24, 12 p.m. ET, Big Ten Network

Michigan Wolverines vs. Ohio State Buckeyes, Nov. 24, 12 p.m. ET, ABC

Indiana Hoosiers vs. Purdue Boilermakers, Nov. 24, 12 p.m. ET, Big Ten Network

Connecticut Huskies vs. Louisville Cardinals, Nov. 24, 12 p.m. ET, Big East Network

Rutgers Scarlet Knights vs. Pittsburgh Panthers, Nov. 24, 12 p.m. ET, ESPN2

Baylor Bears vs. Texas Tech Red Raiders, Nov. 24, 2:30 p.m. ET, FOX

Michigan State Spartans vs. Minnesota Golden Gophers, Nov. 24, 3:30 p.m. ET, Big Ten Network

Oklahoma State Cowboys vs. Oklahoma Sooners, Nov. 24, 3:30 p.m. ET, ESPN

Wisconsin Badgers vs. Penn State Nittany Lions, Nov. 24, 3:30 p.m. ET, ESPN2