Oklahoma State out-scored West Virginia in the first quarter to open up a 31-17 lead over the Mountaineers at half.
Oklahoma State opened the game with 14 unanswered points after a 46-yard rush and 21-yard reception by Josh Stewart to put the Cowboys up 14-0 with 3:07 left in the first quarter.
West Virginia answered on their next possession with a 6-play, 75-yard drive which culminated with a Stedman Bailey 37-yard touchdown reception to cut the Cowboys' lead to 14-7.
Corey Smith returned the ensuing kickoff 61 yards for Oklahoma State's third touchdown of the game which put them up 21-7 at the end of the first quarter.
The Mountaineers scored the first points in the second quarter when Geno Smith completed a 17-yard pass to Tavon Austin for a touchdown to cut the Cowboys' lead to 21-14 with 5:43 left in the half.
Oklahoma State immediately answered on a 4-play, 59-yard drive that concluded with a 48-yard touchdown reception by Blake Jackson. West Virginia fumbled the ensuing Oklahoma State kickoff which setup a 26-yard field goal to give the Cowboys their largest lead of the half, 31-14.
West Virginia ended the half with a 41-yard field goal to cut the Oklahoma State lead to 31-17 after two quarters.