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The West Virginia Mountaineers will be looking for an upset of the No. 12 Oklahoma Sooners when they welcome Oklahoma to Morgantown looking to gain bowl eligibility with a sixth win of the year.
After starting the season strong, the Mountaineers have lost four straight and will need to win one of its final three games to become bowl eligible.
In other local action, the bowl-ineligible Penn State Nittany Lions will take on the Indiana Hoosiers as they try to run its Big Ten record to 5-2 on the year. The Big East's 4-6 Pittsburgh Panthers are off this weekend, but will need to win two straight in the next two weekends to become bowl eligible.
Here is the weekend's entire slate of Big East, Big Ten and Big 12 games:
Temple Owls vs. Army Black Knights, 12 p.m. ET, CBS Sports Network
Rutgers Scarlet Knights vs. Cincinnati Bearcats, 12 p.m. ET, Big East Network
Northwestern Wildcats vs. Michigan State Spartans, 12 p.m. ET, ESPN2
Iowa Hawkeyes vs. Michigan Wolverines, 12 p.m. ET, ESPN
Indiana Hoosies vs. Penn State Nittany Lions, 12 p.m. ET, Big Ten Network
South Florida Bulls vs. Miami Hurricanes, 3 p.m. ET, ESPN3
Wake Forest Demon Deacons vs. Notre Dame Fighting Irish, 3:30 p.m. ET, NBC
Minnesota Golden Gophers vs. Nebraska Cornhuskers, 3:30 p.m. ET, Big Ten Network
Ohio State Buckeyes vs. Wisconsin Badgers, 3:30 p.m. ET, ABC
Purdue Boilermakers vs. Illinois Fighting Illini, 3:30 p.m. ET, Big Ten Network
Texas Tech Red Raiders vs. Oklahoma State Cowboys, 3:30 p.m. ET
Syracuse Orange vs. Missouri Tigers, 7 p.m. ET, ESPNU
Oklahoma Sooners vs. West Virginia Mountaineers, 7 p.m. ET, FOX
Iowa State Cyclones vs. Kansas Jayhawks, 7 p.m. ET
Kansas State WIldcats vs. Baylor Bears, 8 p.m. ET, ESPN