Mel Kiper lists Penn State's Devon Still as the top defensive tackle in the 2012 NFL Draft. Still is almost universally regarded as a first-round pick, and might go as high as the latter part of the top 10.
Here are the Big Ten players in the top five for each position.
Wisconsin's Bradie Ewing, No. 1 fullback
Iowa's Riley Reiff, No. 2 offensive tackle
Ohio State's Mike Adams, No. 4 offensive tackle
Wisconsin's Kevin Zeitler, No. 4 guard
Wisconsin's Peter Konz, No. 1 center
Ohio State's Mike Brewster, No. 2 center
Michigan's David Molk, No. 3 center
Illinois' Whitney Mercilus, No. 4 defensive end
Penn State's Devon Still, No. 1 defensive tackle
Michigan State's Jerel Worthy, No. 5 defensive tackle
Nebraska's Lavonte David, No. 3 outside linebacker
Nebraska's Alfonzo Dennard, No. 4 cornerback
Wisconsin's Philip Welch, No. 2 kicker
Illinois' Derek Dimke, No. 4 kicker
Iowa's Eric Guthrie, No. 5 punter
Obviously, Still is the only Penn State player represented. But he still makes a mark among the Big Ten players above -- he's likely to be drafted higher than any of them, except perhaps Reiff.
For more on the NFL Draft, check out Mocking The Draft.